From what I've seen, a lot of us new players, myself included, end up unlocking the zone doors in the wrong order. While the game wiki does have a text with pictures guide, I wanted to create a video and audio based guide for those of us who are more visual learners!

⭐In-depth Walkthrough of Each Keystone & Door:
➡️https://drive.google.com/file/d/1YX70rbdW8AbDa2McWD9gvT-7yFCMwkI9/view?usp=drivesdk

In summary, here is the order you want to go in and who will give you the keystones you need to do so:

1. Pick up Kybele's breeding task and complete it by giving her a Vulwarg.
   
   ✅Breeding Task: Kybele's Mighty Mate Guide
   ➡️ https://www.patreon.com/posts/first-breeding-105336753

2. ⭐Use key 1️⃣ to unlock Virgin Breaks (The door right next to the keystone and Kybele).

3. In Virgin Breaks, interact with Monarch to pick up her task and complete it by bringing her a Foxen with the "Swift" trait.
   
   ✅ Breeding Task: Monarch's Swift Helper Guide
   ➡️ https://www.patreon.com/posts/monarchs-swift-106015958

4. ⭐Use key 2️⃣ to unlock Pleasure Pastures

5. In Virgin Breaks, talk to the Dragon Queen to pick up her task & complete by bringing her Bovaur Milk; collect the keystone she leaves behind. Make sure you capture some futa and male dragons so you can harvest them for fluids!
   
   ✅ Breeding Task: Milk for the Matriarch Guide
   ➡️ https://www.patreon.com/posts/milk-for-task-106022492

6. In Pleasure Pastures, interact with Autumn to pick up her breeding task. Complete her task by bringing her a Bee with the "Hornball" trait to complete her task.
   
   ✅ Breeding Task: Autumn's Honey Bee Guide
   ➡️ https://www.patreon.com/posts/autumns-honey-106040834

7. ⭐Use key 3️⃣ to unlock The Hivelands

8. Return to The Hivelands, and talk to the Queen Bee to learn about her Flower Problem. Then, go back Autumn and ask her about the flowers. She says she thinks she can help the flowers grow if you bring her 40 Dragon Semen. Return to The Hivelands so you can collect the keystone from the Queen Bee.
   
   ✅ In-Game Task: Hive Queen's Flower Problem Guide
   ➡️ https://www.patreon.com/posts/hive-queens-106444372

9. ⭐Use key 4️⃣ to unlock Cove of Rapture.

10. ⭐Head left to talk to Mirru so you can get access to the pearl in the water (swim from the dock) > Loot the pearl that's near Yasmine.
    
    ✅ In-Game Task: A Pearl for the Mega Slime Keystone Guide
    ➡️ https://www.patreon.com/posts/happy-mega-slime-105911181
    

11. If you continue left, passing Mirru and the dock you will get to the Orc and and Chieftain Xena. Interact with Chieftain Xena to pick up her breeding task. Complete her task to by bringing her a Akabeko (a hybrid between a Foxen and an Ayrshire Bovaur or bull Bovaur).
    
    ✅ Breeding Task: Toy for the Tribe Guide
    ➡️ https://www.patreon.com/posts/breeding-task-106196057
    

12. Interact with Cassie and use the "Uh... meow!" dialogue option, then the "Please yourself in my ****!" dialogue option. Talk with Cassie again, and then use the "What's with the dungeon by the temple?" option. Take the stairs on the left side of Amber-Mae's building to get to the lever that Cassie fixed.
    ⭐To the left of the temple, enter the gate and continue down the halls to the giant slime girl in the dungeon ruins. Interact with the slime and use the "I want you to have this pearl." option. Collect the keystone from her.
    ⭐Return to Virgin Breaks and take the path near the rock the Dragon Queen was sleeping on and use key 5️⃣ to unlock Climax Peak (Titans' area).

13. ⭐Head back to Cove of Rapture, but take the first pathway towards the right. You'll find Apopha Fesssi stuck in the cave. Interact with her to get her task for a Titan.
    
    ✅ Breeding Task: Fat Ass Fesssi's Titan Guide
    ➡️ https://www.patreon.com/posts/breeding-task-105951972
    

14. Completing her task will free Apopha Fesssi from the cave, and she will leave behind a keystone for you. Use key 6️⃣ to unlock the Amorous Hallows door further in the cave.

15. If you jump down into the web, and interact with the Spider Queen, she'll give you a breeding task for an elf.
    
    ✅ Breeding Task: Widow's Juicy Elf Guide
    ➡️ https://www.patreon.com/posts/breeding-task-106569969
    
     ⭐Climb up the rocks to get to the side with the portal and follow the stairs down til you get to the lava pit.
    ⭐⭐If you don't like the tentacles in the world you can jump across the rocks in the lava and talk to Sloth; interacting with all of her dialogue options will allow you to turn off the tentacles.

16. ⭐If you continue on the path towards the right, you will find the bats. Use key 7️⃣ to unlock the Esoteric Glades door; you will find the Goblins and Elves in this area.

17. ⭐Use key 8️⃣ to unlock the Sultry Plateau door (left path up ruins in Hivelands) to access the Nekos.

18. Continue exploring and you'll come across Petra, the bunny girl on the side of the cliff to get one last breeding task.
    
    ✅ Breeding Task: Practice Dragon for Petra Guide
    ➡️ https://www.patreon.com/posts/breeding-task-106572453
    

19. ⭐If you've completed all breeding tasks and traded pearl for keystone, you should have enough to unlock Lewd Desert & Sensual Heavens and Moaning Crag.
    
    ➡️Use key 9️⃣ to unlock Lewd Desert door within Sultry Plateau and use the orb in Lewd Desert (Harpies and Starfallen nephelym), that is up top with the Starfallen to get to Sensual Heavens (Seraphim nephelym).
    
    ➡️Use key 🔟 to unlock Moaning Crag (Demon nephelym) door within the Amorous Hallows.

ℹ️ Alternatively >>>

1. Pick up Kybele's breeding task and complete it by giving her a Vulwarg.
   
   ✅Breeding Task: Kybele's Mighty Mate Guide
   ➡️ https://www.patreon.com/posts/first-breeding-105336753

2. ⭐Use key 1️⃣ to unlock Pleasure Pastures

3. In Pleasure Pastures, interact with Monarch to pick up her task and complete it by bringing her a Foxen with the "Swift" trait.
   
   ✅ Breeding Task: Monarch's Swift Helper Guide
   ➡️ https://www.patreon.com/posts/monarchs-swift-106015958

4. ⭐Use key 2️⃣ to unlock the Hivelands.

5. In Pleasure Pastures, interact with Autumn to pick up her breeding task. Complete her task by bringing her a Bee with the "Hornball" trait .
   
   ✅ Breeding Task: Autumn's Honey Bee Guide
   ➡️ https://www.patreon.com/posts/autumns-honey-106040834

6. ⭐Use key 3️⃣ to unlock Virgin Breaks (Dragons)

7. In Virgin Breaks, talk to the Dragon Queen to pick up her task & complete by bringing her milk; collect the keystone she leaves behind. Make sure you capture some futa and male dragons so you can harvest them for fluids!
   
   ✅ Breeding Task: Milk for the Matriarch Guide
   ➡️ https://www.patreon.com/posts/milk-for-task-106022492

Intro to Keystone Walkthrough (Streamable)