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April 27, 2026

#553 - The Worst Urine Sample

Comments (171)

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Cristian Mejia · July 28, 2026

I H Bill

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Lana Faraj · June 12, 2026

Men nmzzmzmlzkzkkzbjkkk zzz

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Leta · June 1, 2026

I could have sworn we had this similar pee convo before 😭

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Leta · June 1, 2026

LMAO bc I watched this already

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Jo · May 29, 2026

you’re not supposed to use head and shoulders basically ever it’s so bad for your scalp

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Hal · May 21, 2026

the disrespect from Frankie about hufflepuff and slytherin is crazy

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dion · May 19, 2026

hello

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Ellie Vranesevic · May 13, 2026

I love the “ant writes down time stamp titles” bit FAR too much 😆

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Shep · May 10, 2026

If yall do a D&D episode, tell Hank Green to get in touch with Brennan Lee Mulligan to DM PUH-LEASE

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Ta'Shay Lexington · May 6, 2026

As intelligent Frankie is, he uses the word like more than he used laborious 😂

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Raquel Mazza · May 6, 2026

I’m curious on how they control the camera’s. Whenever Ant is about to plug his IG he’s always looking at something to see if he’s going to get cut off.

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Megan Salisbury · May 6, 2026

So what you’re saying is that you have a picture of Frankie’s wife in your nightstand? 🤨😂

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Jordan Martinez · May 6, 2026

It’s 65 dollars for a wand unless you get a special one I have a few

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Lindsay Wieser · May 4, 2026

The “you’re my lobster” thing is from the show Friends

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Amanda Dufault · May 4, 2026

Why can’t I see the video?

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KatKev · May 4, 2026

I watched half of it earlier today and now it's gone. They must have gottwn flagged for something

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Elise Dickey · May 2, 2026

CRAB AND BARF 😭

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Genkai D. Wiener · May 2, 2026

I’d ABSOLUTELY love a “what’s in Frank’s bins?” Episode lmao

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Amy Young · May 2, 2026

A urinalysis is most accurate when urine is collected using the “clean catch” method, which is when you start to pee and then collect the sample mid stream. This helps minimize contamination from the urethra. When collecting a sample to test for STDs, you pee directly into the cup first and then void the rest into the toilet. STD testing (gonorrhea, chlamydia, trichomonas) is best tested with the bacteria from the urethra. Also, most tests can be easily performed with a small sample ☺️

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Paige · May 2, 2026

nobody mentioned how life altering getting dr. bronners soap in your eye is. i swear it rivals pepper spray. my mom has used it since the 80s. but yes, it is vegan, biodegradable and environmentally friendly.. it’s a great soap, but NEVER get it in your fuckin eyes.

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Brooke Scott · May 1, 2026

all I can think of is Ross Geller from friends when someone talks about Paleontology LOL

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Anthony Geremia · April 30, 2026

Love that hat Frankie - where is it from?

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Katie J. · April 30, 2026

Crab and BARF 😂😂😂

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Ty Engler · April 30, 2026

Dudes… you live in NY. Go to the Harry Potter store in manhattan and they have like 200 different wands you can get for way cheaper lol

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Maybellene Huerta · April 30, 2026

The first baseball game I went to as a kid, a player hit a home run and an older man caught it and gave it to me. I was maybe 5 or 6 years old. I’ll never forget it. I still have the ball over 20 years later

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Miia · April 30, 2026

You know what we need, an episode of ant reading the notes he takes and the boys trying to figure out when it’s from - because those notes would be wild haha 😂

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Molly burgesser · April 30, 2026

Dr. Bronner’s was a trivia answer for me tonight, so thanks boys🫡

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Kaylee C · April 30, 2026

wands are like 65-85$!

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Abigail Sorrell · April 29, 2026

Frankie… it’s Tear free, not tear free. As in, your hair done split or tear. Not it won’t make tear if you get it in your eyes…. Please tell me I’m not the only one who knew this….

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Trinity Vessells · April 29, 2026

Please have Hank Green on an episode!🙏🏻

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Emily Moreno · April 29, 2026

as a dental assistant, PLEASE do not use this 18-in-1 soap on your teeth

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Jemwell Madarang · April 29, 2026

i want shane to be your guest 😔❤️

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Ericha Grace · April 29, 2026

Frankie should check out the podcast Ologies

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Allison Goodman · April 29, 2026

It’s okay Frankie, I thought lobsters mated for life too

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Bailey Raab · April 29, 2026

As someone getting a doctorate in archaeology, I do think they would break me.

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Lesli · April 29, 2026

Frank needs a junk journal

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Alondra Nunez · April 28, 2026

a whole convo about penguins I love it

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Danise Plaza · April 28, 2026

i HATE frankie crankin it staring at Joe and absolutely cracking up about it 🤣🤣🤣

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Courtney · April 28, 2026

My multivitamin turns mine and my husbands pee neon green. Usually just the first couple of pees after the pill. I was in the military and was terrified I'd have neon pee for a random drug test that you have to hold above your head infront of everyone 🫠

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Marissa Batey · April 28, 2026

The reason you start peeing a little before you pee in the cup is because it’s supposed to be a clean catch lol. The initial stream gets rid of any surface bacteria/cells that could interfere with testing

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Janna J · April 28, 2026

Was it Lab Corp? My local Lab Corp has those same styrofoam coffee pee cups. I also didn’t pee enough the last time bc I peed before I left the house. I’m with ya Frank. You’re not alone lol 😆

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Nycole Kuiken · April 28, 2026

Dr Bronners is so fantastic.

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Briana · April 28, 2026

The leaky cauldron is in London they’re talking about the three broomsticks that’s in hogsmead

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Grace · April 28, 2026

Hufflepuff here <3

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MaKayla Michaels · April 28, 2026

BRING IN the genius of random stuff. Like, in their feild. So like.... The coolest and top engineer. The best game developer or animator The best bird watcher in y'all's area A really neat marketing instructor Omg a really good preschool teacher and a college English professor This might be ideas for a nerdier guest podcats lol

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a lesbian with a sword · April 28, 2026

Neil Degrasse Tyson was recently on the I Never Liked You Podcast to promote his book and he survived Nick and was actually very patient. if he can teach nick about clouds, saturn, and what dying in a black hole would be like then he can definitely teach you guys some space shit

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Jimmy · April 28, 2026

I’m very curious if there was a “pre-show” before the Oz performance.

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XpeepingtayX · April 28, 2026

I’m lost who is Nicole?

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Mckayla O'Sullivan · April 28, 2026

It just kept cummin lmfao!!!!!

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Kyla Tigranes · April 28, 2026

Nicole Kidman’s hands remind me of how my grandmother’s hands were. She had Marfan’s Syndrome. 👀

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trisha conyers · April 28, 2026

I would kill for a Joe & Frankie/Willne & James collab😭🖤

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brooke · April 28, 2026

my dad and brother went deep sea fishing and my brother refused to piss on or off the side of the boat with my dad around so my dad had to drive him to the closest island for some privacy 😂 being pee shy is soooo real

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Chloé · April 28, 2026

There’s a lot of people who go to Disney World Japan rather than CA OR FL because it’s SO much cheaper

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Chloé · April 28, 2026

I wanna see y’all do the things that y’all talked about on the podcast such as Edward 40 hands, trying exotic fruit, trying MRE’s, etc. it’s nice when y’all have guest but yall have talked about so many different episode ideas that are amazing

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Sarah Brown · April 28, 2026

Crabbe and Barf took me out 😭

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Alexis patnode · April 28, 2026

PLZ SEE THIS! I’m waiting on joeys turn of writing a funny script that Frankie can’t laugh while acting it. That was seriously one of the best episodes yall have put out!!

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Annie Kate · April 28, 2026

You guys need to get Bill Nye the Science Guy! He’s SO fun!

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Maddie · April 28, 2026

ahh yes, the B vitamin neon yellow green piss 💚

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Grubella · April 28, 2026

Please have Hank Green 🙏🏻

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Ally T · April 28, 2026

In the future, if you guys continue to talk about Harry Potter, could you at least give a little statement about how you don’t support JK Rowling? Her blatant transphobia and calls for legislation to essentially eliminate trans people from society has been so harmful and dangerous. I get that millions of people still love Harry Potter, but she still makes so much fucking money off of the series, and is using that money to fund campaigns against trans people. It’s reprehensible, and I know the BY team supports trans people.

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Jessy King · April 28, 2026

Hey Ally, it's not that serious and everything doesn't need to be a political statement. If you know they support trans, that should be enough to make you feel good. This is a comedy podcast. Enjoy!

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Paige · April 28, 2026

@Frank I also keep bins and bins of nostalgia from my life and I’ve been making quilts out of tshirts from different eras of my life so that I still have them but they’re not just in storage :)) there are also ppl who you can send shirts to and they’ll quilt them for you :)

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Val · April 28, 2026

lmaoooo the steinway comment, so random

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Zack Bartlett · April 28, 2026

Anyone else yelling at their phone everytime they get something wrong about Harry Potter? 😂

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mckenna · April 28, 2026

they need jeremy wade on here the river monster guy

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Simone Messervey · April 27, 2026

Hi, hairstylist here! Never ever use Head and Shoulders. All it does is pack down dandruff. It doesn’t help get rid of it. That is why Ant says when he uses other shampoos his dandruff “comes back.” It was never gone to begin with, just masked. Conditioner should be used. Mid-length to ends for most hair. If you find your scalp is dry then use conditioner scalp to ends. It acts as a moisturizer for the scalp. If it’s too heavy and weighs the hair down then get a volume or thickening conditioner. Or alternate from mid-length to ends one day, then scalp to ends the next.

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LMFB · April 27, 2026

Y'all....Dr. Bronners soap has to be diluted A LOT to be used on the body. I use that ship to mop my floors and clean my toilet, sometimes add a bit into my laundry. I have and will NEVER use it on my body. It's so concentrated, I just don't think it is safe.

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Morgan · April 27, 2026

I was a nurse in a prison for awhile… long story short, I had a guy in sick call that told me he put a “chunk” of his bar soap” IN his pee hole to clean it, and then was concerned he had weird discharge…. I was like yeaaah………….. don’t do that? How bout dat

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Maicee · April 27, 2026

wait… why was i thinking Madagascar before you even said it 😅🙃

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Ally T · April 28, 2026

ME TOO!!!

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Shauna · April 27, 2026

For the conditioner thing- using it on all of your hair can just make your scalp greasier sooner, and could cause product buildup. Not really harmful per se

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Simone Messervey · April 27, 2026

It won’t cause buildup. And it can be used on the scalp if the scalp is dry! When skin is dry we moisturize, when scalp is dry we condition

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Destinee James · April 27, 2026

Being a hobo Johnson fan and listening to this episode is difficult lol

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Mollie smith · April 27, 2026

Ant should post the time codes a day before the ep drops and we can all guess wtf the boys are going to be talking about.

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Paige Blackdeer · April 27, 2026

I used dr bronners on the worst stain ever and after like two washes it was gone I swear that soap is magic

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Meredith Wilson · April 27, 2026

…still waiting for Joe Jonas to be a special guest

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Alexis patnode · April 27, 2026

It pisses me off that Frankie didn’t comment at all on how great the original caption was on the penguin video but then Joe reads the stupid “go left where nothing is right comment” and he freaks out and says damn that hits like really dude 😂

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Jenell · April 27, 2026

The part with Joey not remembering Goyle’s name is something I’d never think to be relatable but my sister and I never remembered his name and would always say “Crab and Privates” 💀💀💀

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Hch · April 27, 2026

Omg I’m 20 mins in this is the funniest episode I’ve ever seen lmao

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Autumn · April 27, 2026

what about Dr. Dre

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Maddy · April 27, 2026

As a hairstylist- please don’t use head and shoulders every wash😭😭 unless you have crazy dandruff, and at that point just get some medicated shampoo lmfaoo

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Rose Lemieux · April 27, 2026

Dr. Bronner’s is 100% essential oils so it’s safe for legit anything. I’ve used the peppermint one for YEARS and currently use it for hand soap, body wash, and shampoo. It’s incredible.

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Loren Erway · April 27, 2026

Joe and Ant talk to a Scientist every day.

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Cass Daley · April 27, 2026

I’m a hufflepuff…damn 😭😂

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de · April 27, 2026

holy shit i have bronchitis right now and frankie jerking off with that long ass piece of trash almost made me throw up from laughing 🤣🤣🤣 wtf

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Daisy · April 27, 2026

You’re telling me Joe lives in Brooklyn and doesn’t know Dr. Bronners?

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Morgan Giang · April 27, 2026

I hope Ant hears that he was right about the HP taverns lol. the Leaky Cauldron is on Diagon Alley in London, not Hogsmeade. AND that Aberforth’s place IN Hogsmeade is called the Hog’s Head and has a big hog on the sign. ANT, DON’T LET FRANKIE GASLIGHT YOU INTO THINKING YOU DON’T KNOW WHAT YOU’RE TALKING ABOUT!! we love you!!

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Zack Bartlett · April 28, 2026

Thank you! Every time these guys get something wrong about Harry Potter, I lose it 😂😂

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Kase Ford · April 27, 2026

The fact that Frankie says the word "like" for every other word, drives me a bit insane lol

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AJ Noel · May 4, 2026

Mya needs to work on an edit with a counter showing how many times he says it in one video😂

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LadyB · April 27, 2026

Frankie jerking off with a piece of trash🤣

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Harambe · April 27, 2026

Omfg this episode is the best 😂😂😂

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Ève-Marie Lapierre · April 27, 2026

Hey the access is restricted why can’t I watch the ep on here anymore?

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Angel Stacey · April 27, 2026

hairdresser here haha conditioner should be used antonio! it is intended for mid shaft of the hair to ends for longer hair but should be used. if you feel like your hair gets flat from it ant, the one you’re using is too heavy for your hair:) looks like you have fine hair need something not too heavy!

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Angel Stacey · April 27, 2026

also pls don’t use that soap as your shampoo dear lord and don’t use 3 in 1 either there is shampoo and conditioner specific for hair types!

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K1RAMEKI · April 27, 2026

it'd be really funny if they got nicole on an episode just talking about nutrition and shit like that considering she has a masters in public health lmao also 18 in 1 soap is so fucking insane to me im surprised its not also used as lube

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Allen Reed · April 27, 2026

We saw the episode already guys with dr.oz

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Anna Stafford · April 27, 2026

when they were explaining the trick OZ did on ant... i immediately thought of madagascar as my first choice. wtf. im shakin.

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cassiejo goad · April 27, 2026

justice for Hufflepuffs.

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Sarah 🐦 · April 27, 2026

You can tell when Joe is truly appalled because he becomes possessed by Gilbert Gottfried's ghost

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Heavenly Morton-Pena · April 27, 2026

How many years before we can get Miles on the show I just know he’s got some good stories on Frank

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Sophie · April 27, 2026

I hope they react to all the Tomodachi Life tik toks of them at some point 😂

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Alberto Sotelo · April 27, 2026

Frank not realizing that the “you’re my lobster” line is a Phoebe quote from friends and thinking it’s scientific fact is hilarious to me

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Derek · April 27, 2026

We still need the Hank Green episode !!!!!!!!!!!!!

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Heavenly Morton-Pena · April 27, 2026

Have you guys not seen FRIENDS he’s her lobster 🦞

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Jaden Field · April 27, 2026

“I like my piss” -Frank 2026

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Nicole · April 27, 2026

hank green would be a good guest too

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Nicole · April 27, 2026

becca should be the next guest on the show!

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Grace DePietro · April 27, 2026

I'm going to disney for the first time in october and I've cried almost every day at the thought that I'm going to see the millennium falcon

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Jenell · April 27, 2026

I love this for you girl ❤️❤️ live your childhood dreamsssss

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Brittany McElligott · April 27, 2026

The Leaky Cauldron is in Diagon Alley not Hogsmeade. The Three Broomsticks in is Hogsmeade

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Michael · April 27, 2026

Came to say exactly this, good to know there’s a person of culture around

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Jax · April 27, 2026

The Hufflepuff slander cuts me like a knife every time 🥲🥲

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Katie · April 27, 2026

They do that because its supposed to be mid stream for a 'clean catch' often times when u first starting peeing there could be false bacterial coming out and it can skew the results of the urine test creating false positives for a UTI or other bacteria 🙂 Franky we aren't judging your urine amount hahahaha I promise. Also that soap is the besttttttt

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Andie · April 27, 2026

There is a new park at Universal! It's called Epic Universe and you guys should check it out if you go!

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Cat Alewine · April 27, 2026

I used the do the same thing as Joe— just standing in the shower with water and not using soap. My mom literally would sit on the toilet outside of my shower to make sure she heard soap bottles opening and closing, and could smell the soap.

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Melody Flack · April 29, 2026

THIS IS KILLING MEEEEE LMAO

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Kaile Kwan · April 27, 2026

Piss bottles in the car, insane lmao

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Mack · April 27, 2026

I love this week in advance thing😁😁😁

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Nathan v. · April 27, 2026

It's called huffle*puff* for a reason my guy, that's where you'll find me lol

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Kerry Cortes · April 27, 2026

The Dr. Bronner soap part is my new favorite segment 🤣🤣

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Cat Alewine · April 27, 2026

I use the Dr. Bronners peppermint soap and I can attest… don’t get it near things you don’t want to burn

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Anthony · April 27, 2026

Neil Thegrassbison

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Kaitlyn Kent · April 27, 2026

It’s okay, Frankie. You pissed just enough. They need way less than what you think. ❤️ Sincerely, a woman who’s apologized for “not filling the cup up all the way” 100,000 times. Stay strong, soldier. 🫡

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Leah Murphy · April 27, 2026

The consistency that BY brings to my life. Appreciate ya’ll!!

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Sarah H · April 27, 2026

Yall gotta get Josh Gates from expedition unknown. Treasure hunter doctor episode

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Molly · April 27, 2026

The Leaky Cauldron isn't in Hogsmeade. The pub in Hogsmeade is called The Three Broomsticks.

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Chelsea · April 27, 2026

there is a hogs head too

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Amanda Thomas · April 27, 2026

Any chance of a tarot episode 👀 you guys could try to read each others cards

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Kathryn Mosser · April 27, 2026

As a Slytherin… we don’t claim Salazar Slytherin’s hateful energy lol We are also proud, cunning, loyal, slick, etc. Snape was a Slytherin and he was in love with Lily. He was a bully too BUT I DIGRESS 😭😭

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Zack Bartlett · April 28, 2026

Thank you for sticking up for us slytherins! We’re good people!

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Bobbyboi1017 · April 27, 2026

Can you do a potter more episode where you see your houses, patronus, and wand type?

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Paige · April 27, 2026

please, no, they’ve talked more than enough about HP

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Katelyn Montague · April 27, 2026

ive used dr bronners as a face wash for the last 10 years and im a ride or die for it as someone who normally has acne prone and oily skin

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Becca S · April 27, 2026

Neil deGrasse Tyson is a rapist, do not put him on the show

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FanduelFanatic · April 27, 2026

What is with you people? 0 evidence of that.

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Reghan · April 27, 2026

I promise you, as a nurse, as long as we have enough urine to run the screen (which is really not much) we don’t care lmaoooo

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Jordan · April 27, 2026

I’ve used that 18 in 1 soap..can confirm it felt like my balls were on fire then immediately teleported to Pluto

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Lauren Salas · April 27, 2026

Also… one of the medications you can use for a UTI turned your urine like bright orange. The first time I ever used it was extremely alarming 😂

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Molly · April 27, 2026

I learned about this when I was like 7. My grandma said "molly come look how pretty my pee is?" Lmao it honestly did look like a sunset

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Lauren Salas · April 27, 2026

Idk why but the word piss bothers me beyond belief. I haaaaate ittt. It’s definitely a me problem 😂

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ali · April 27, 2026

Alright. Not an episode to eat breakfast with. Noted. "Just takin'... Notes" *Ant voice*

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888 · April 27, 2026

Thank you for commenting bc that's exactly what I was gonna do lmao Hope you have a great day, queen!

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Tanner Lohse · April 27, 2026

There’s no difference between the regular eps and the Patreon ones, let’s just be honest here

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Tasha · April 27, 2026

Literally was thinking that the other day. Sometimes the regular episodes are even better than the patreon ones

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Molly · April 27, 2026

No, you do not have to start the stream first. I have to pee in a cup every single month of my life. Just piss in the cup.

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Darian · April 27, 2026

Theres two people in these comments with a medical profession that are saying the exact opposite of this 💀

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Dawn · April 27, 2026

Yous should have your ladies come on for a show!

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K1RAMEKI · April 27, 2026

i would pay good money for an episode with becca and nicole so i second this

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nj · April 27, 2026

Happy Monday !!!!

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DonnyFromDetroit · April 27, 2026

Frankie should totally get into junk journaling!

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Grace Barger · April 27, 2026

ANT COLONY RISE UP 🐜🐜

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HungChachi · April 27, 2026

Stay away from that 18-in-1 soap

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TheDoctorKelp . · April 27, 2026

Good morning Ant 🐿️

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Rach. 🌻 · April 27, 2026

Just googled Dr bronner.. it’s in Australia and it has different products.. not the same bottle of soap for everything 🤣

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Probowtie87 · April 27, 2026

The penguin was runnninnnnGGG

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Caitlin · April 27, 2026

Joe only being about to think of 3 things in the whole world to clean is so concerning 😭

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Jen Spielman · April 27, 2026

Medical Lab Scientist here... we dont need as much urine as you think, Frankie, your pee quantity is perfectly normal lol. And Joe, PLEASE do a "clean catch"! The reason we ask for that is so that your normal skin flora does not contaminate the sample which could lead to a misdiagnosed UTI that isn't actually there. ❤️❤️

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Anna Sons · April 27, 2026

Dr. Bronner’s is no joke 😂

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Maddie · April 27, 2026

Hi, nurse here, we ask you to pee first and collect midstream because our urinary tract is sterile and we want to flush out any old remnants of bacteria that could affect your screening

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Cristina Noel · April 27, 2026

A wizard shit 😂😂😂

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Ash · April 27, 2026

good morning boys, especially Ant 📢

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Jaded · April 27, 2026

you guys will never understand how much I appreciate yall being on the east coast as well as giving us steady early episodes😭 I love waking up for work and not having to wait all day

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marie · April 27, 2026

I be forgetting they post Mondays and get so hypeeeee 😝

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Jaden M · April 27, 2026

I wish I was still sleeping 😪

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Chloe D Mutch · April 27, 2026

Best notification to receive that there is another video

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Ian Sharp · April 27, 2026

love you frankie

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Anthony Molina · April 27, 2026

Good morning Everybody🫡

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Markie Roye · April 27, 2026

Only reason I like mondays

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Emily watson · April 27, 2026

Opened the app AS it’s posted What a great day

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Jack Harrison · April 27, 2026

Happy Monday yall